Outcome of treatment
Every seventh partnership in Germany is without children involuntarily. And one third of all couples experience a twelve month long episode of childlessness. And yet the chances of becoming pregnant for a young and healthy couple at the age of 20 is 40% for every cycle. However, the age of the woman matters more regarding the success rate. This is why the chances of becoming pregnant decreases by 15 – 20 % with every cycle at the age of 30 – 35.
The chance of success regarding the ART treatment also differ and depend on the age and pre-existing illness.
Every year, the German IVF Register (DIR, Deutsches IVF Register) calculates the average prospects regarding pregnancy rates:
• IVF: about 10% for women under the age of 40,
• ICSI: about 29-36% for women under the age of 40
The chances of a positive outcome of treatment in IVF, ICSI treatment rise with the number of every transfer made. We can show the same outcome at our doctor’s office. 65% of couples have a child after 6 cycles.
Clinical pregnancies per transfer. The decisive point, however, is the chances for success of a child being born. Therefore not only the probability of the women becoming pregnant is to be taken into consideration, but also forecasts about the further development until the birth. Only the birth of your own child is what you and we would call a successful treatment.
With an ideal subpopulation of patients quite high birth rates are possible. However, if the results of all patients obtained over a longer period of time is taken together, a remunerated top IVF-center with very good result worldwide will, in the best of all cases, reach a birth rate per cycle commenced which equals the possible natural birth rates for healthy and fertile couples, which is about 20%. The results of the most IVF-centers lag behind these possibilities.
No IVF-center of the world can get ahead nature: More than 50% of the egg cells of women at only 35 years show a maldistribution of chromosomes and will thus decay after fertilization (cf. polar body diagnostics). And there are also losses due to the fertilization of healthy egg cells with chromosomal defective sperm cells and losses due to a maldistribution of chromosomes in the further development of the early embryos. Only few pre-nucleus stages have to potential to become a blastocyst (embryo five days after fertilization) and even less will really become a child. In the statistic average only three of fifteen pre-nucleus stages have the potential to develop into a blastocyst. And in the statistic average only one of three blastocysts has in turn the potential to develop into a human being, a child.