Outcome of treatment
In Germany, every 7th to 10th partnership is affected by unwanted childlessness. And 1/3 of all couples experience a period of childlessness of at least 12 months. At the same time, the probability of pregnancy per cycle without treatment is 40% for a healthy, young couple of 20 years of age. However, the woman's age plays a major role in the success rate and the probability of pregnancy per cycle decreases to 15-20% at the age of 30-35 years.
The chances of success of an ART treatment are also very different for each individual and depend on age and any previous illnesses. The German IVF Register (DIR) calculates the average success rate for the pregnancy rate each year:
- Intercourse at the optimal time and insemination: approx. 10% for women under 40 years of age
- IVF, ICSI: approx. 29-36% for women under 40 years of age
With IVF, ICSI treatment, the success rate increases with the increasing number of transfers. We have also obtained these results in our doctos's office. After 6 cycles, 65% of couples succeed in having a child.
Source: Andrew, D. A. S. et. al.: Live-birth rate associated with repeat In Vitro fertilization Treatment Cycles; JAMA. 2015, 314(15):2654-2662).
When asking about the chances for success of the treatment the couples wishing to have a child are most commonly told the pregnancy quota per transferred embryo.
We also are happy to present you our excellent birth quotas per transferred embryo in a personal appointment.
The graphic is based on the evaluation of the prospective German IVF Register (GIR)*.
Clinical pregnancies per transfer. The decisive point, however, is the chances for success of a child being born. Therefore not only the probability of the women becoming pregnant is to be taken into consideration, but also forecasts about the further development until the birth.
Only the birth of your own child is what you and we would call a successful treatment. We are proud about birth rates per stimulation cycle (according to GIR*) which can also compete with the treatment results of international top-fertility centers.
The prospective German IVF Register GIR is the most comprehensive and the strictest register worldwide. Each case of treatment has to be registered by the 7th day of stimulation at the latest; Subsequent registrations or changes are not possible or are recorded comprehensively, so that data manipulation in the DIR is almost impossible. Central GIR-evaluations of the single IVF-groups are the quality assurance instrument determined by the respective Medical Association's professional code of conduct.
With an ideal subpopulation of patients quite high birth rates are possible. However, if the results of all patients obtained over a longer period of time is taken together, a remunerated top IVF-center with very good result worldwide will, in the best of all cases, reach a birth rate per cycle commenced which equals the possible natural birth rates for healthy and fertile couples, which is about 20%. The results of the most IVF-centers lag behind these possibilities.
No IVF-center of the world can get ahead nature: More than 50% of the egg cells of women at only 35 years show a maldistribution of chromosomes and will thus decay after fertilization (cf. polar body diagnostics). And there are also losses due to the fertilization of healthy egg cells with chromosomal defective sperm cells and losses due to a maldistribution of chromosomes in the further development of the early embryos. Only few pre-nucleus stages have to potential to become a blastocyst (embryo five days after fertilization) and even less will really become a child. In the statistic average only three of fifteen pre-nucleus stages have the potential to develop into a blastocyst. And in the statistic average only one of three blastocysts has in turn the potential to develop into a human being, a child.